by Thomas M Campbell and Scott E Liebman
Abstract:
A 69-year-old man with type 2 diabetes, hypertension and stage 3 chronic kidney disease (CKD), hyperphosphataemia and borderline hyperkalaemia presented to an office visit interested in changing his diet to improve his medical conditions. He adopted a strict whole-foods, plant-based diet, without calorie or portion restriction or mandated exercise, and rapidly reduced his insulin requirements by >50%, and subsequently saw improvements in weight, blood pressure and cholesterol. His estimated glomerular filtration rate (eGFR) increased from 45 to 74 mL/min after 4.5 months on the diet and his microalbumin/creatinine ratio decreased from 414.3 to 26.8 mg/g. His phosphorus level returned to the normal range. For individuals with CKD, especially those with obesity, hypertension, or diabetes, a strict, ad libitum whole-food, plant-based diet may confer significant benefit, although one must consider potential limitations of a creatinine-based GFR equation in the face of significant weight loss.
Reference:
Plant-based dietary approach to stage 3 chronic kidney disease with hyperphosphataemia. (Thomas M Campbell and Scott E Liebman), In BMJ Case Rep, volume 12, 2019.
Bibtex Entry:
@article{Campbell:2019aa,
abstract = {A 69-year-old man with type 2 diabetes, hypertension and stage 3 chronic kidney disease (CKD), hyperphosphataemia and borderline hyperkalaemia presented to an office visit interested in changing his diet to improve his medical conditions. He adopted a strict whole-foods, plant-based diet, without calorie or portion restriction or mandated exercise, and rapidly reduced his insulin requirements by >50%, and subsequently saw improvements in weight, blood pressure and cholesterol. His estimated glomerular filtration rate (eGFR) increased from 45 to 74 mL/min after 4.5 months on the diet and his microalbumin/creatinine ratio decreased from 414.3 to 26.8 mg/g. His phosphorus level returned to the normal range. For individuals with CKD, especially those with obesity, hypertension, or diabetes, a strict, ad libitum whole-food, plant-based diet may confer significant benefit, although one must consider potential limitations of a creatinine-based GFR equation in the face of significant weight loss.},
address = {Family Medicine, University of Rochester Medical Center, Rochester, New York, USA thomas_campbell@urmc.rochester.edu.; Nephrology, University of Rochester Medical Center, Rochester, New York, USA.},
auid = {ORCID: 0000-0003-4449-8229},
author = {Campbell, Thomas M and Liebman, Scott E},
cois = {Competing interests: TMC receives royalties from general interest books published about nutrition and health. He also has received honoraria and travel reimbursement for general interest lectures on the topic of plant-based nutrition and health. He has received research support from the Highland Hospital Foundation, which has received donations from the T Colin Campbell Center for Nutrition Studies, the Thomas Hormel Foundation and numerous individuals.},
copyright = {{\copyright}BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.},
crdt = {2019/12/26 06:00},
date = {2019 Dec 23},
date-added = {2023-06-08 15:45:18 +0100},
date-modified = {2023-06-08 16:17:42 +0100},
dcom = {20200508},
dep = {20191223},
doi = {10.1136/bcr-2019-232080},
edat = {2019/12/26 06:00},
issn = {1757-790X (Electronic); 1757-790X (Linking)},
jid = {101526291},
journal = {BMJ Case Rep},
jt = {BMJ case reports},
keywords = {Plant-Based Diet,},
language = {eng},
lid = {10.1136/bcr-2019-232080 {$[$}doi{$]$}; e232080},
lr = {20200508},
mh = {Aged; Diabetes Mellitus, Type 2/complications; Diabetic Nephropathies/complications; *Diet, Vegetarian; Humans; Hyperphosphatemia/*diet therapy; Male; Obesity/complications; Renal Insufficiency, Chronic/*diet therapy; Treatment Outcome},
mhda = {2020/05/10 06:00},
month = {Dec},
number = {12},
oto = {NOTNLM},
own = {NLM},
phst = {2019/12/26 06:00 {$[$}entrez{$]$}; 2019/12/26 06:00 {$[$}pubmed{$]$}; 2020/05/10 06:00 {$[$}medline{$]$}},
pii = {12/12/e232080; bcr-2019-232080},
pl = {England},
pmc = {PMC6936381},
pmid = {31874846},
pst = {epublish},
pt = {Case Reports; Journal Article},
sb = {IM},
status = {MEDLINE},
title = {Plant-based dietary approach to stage 3 chronic kidney disease with hyperphosphataemia.},
volume = {12},
year = {2019},
bdsk-url-1 = {https://doi.org/10.1136/bcr-2019-232080}}