by Juan J Carrero, Ailema González-Ortiz, Carla M Avesani, Stephan J L Bakker, Vincenzo Bellizzi, Philippe Chauveau, Catherine M Clase, Adamasco Cupisti, Angeles Espinosa-Cuevas, Pablo Molina, Karine Moreau, Giorgina B Piccoli, Adrian Post, Siren Sezer and Denis Fouque
Abstract:
Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus on the quantity of nutrients consumed. Without appropriate dietary counselling, these restrictions can result in a low intake of fruits and vegetables and a lack of diversity in the diet. Plant nutrients and plant-based diets could have beneficial effects in patients with CKD: increased fibre intake shifts the gut microbiota towards reduced production of uraemic toxins; plant fats, particularly olive oil, have anti-atherogenic effects; plant anions might mitigate metabolic acidosis and slow CKD progression; and as plant phosphorus has a lower bioavailability than animal phosphorus, plant-based diets might enable better control of hyperphosphataemia. Current evidence suggests that promoting the adoption of plant-based diets has few risks but potential benefits for the primary prevention of CKD, as well as for delaying progression in patients with CKD G3-5. These diets might also help to manage and prevent some of the symptoms and metabolic complications of CKD. We suggest that restriction of plant foods as a strategy to prevent hyperkalaemia or undernutrition should be individualized to avoid depriving patients with CKD of these potential beneficial effects of plant-based diets. However, research is needed to address knowledge gaps, particularly regarding the relevance and extent of diet-induced hyperkalaemia in patients undergoing dialysis.
Reference:
Plant-based diets to manage the risks and complications of chronic kidney disease. (Juan J Carrero, Ailema González-Ortiz, Carla M Avesani, Stephan J L Bakker, Vincenzo Bellizzi, Philippe Chauveau, Catherine M Clase, Adamasco Cupisti, Angeles Espinosa-Cuevas, Pablo Molina, Karine Moreau, Giorgina B Piccoli, Adrian Post, Siren Sezer and Denis Fouque), In Nat Rev Nephrol, volume 16, 2020.
Bibtex Entry:
@article{Carrero:2020aa,
abstract = {Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus on the quantity of nutrients consumed. Without appropriate dietary counselling, these restrictions can result in a low intake of fruits and vegetables and a lack of diversity in the diet. Plant nutrients and plant-based diets could have beneficial effects in patients with CKD: increased fibre intake shifts the gut microbiota towards reduced production of uraemic toxins; plant fats, particularly olive oil, have anti-atherogenic effects; plant anions might mitigate metabolic acidosis and slow CKD progression; and as plant phosphorus has a lower bioavailability than animal phosphorus, plant-based diets might enable better control of hyperphosphataemia. Current evidence suggests that promoting the adoption of plant-based diets has few risks but potential benefits for the primary prevention of CKD, as well as for delaying progression in patients with CKD G3-5. These diets might also help to manage and prevent some of the symptoms and metabolic complications of CKD. We suggest that restriction of plant foods as a strategy to prevent hyperkalaemia or undernutrition should be individualized to avoid depriving patients with CKD of these potential beneficial effects of plant-based diets. However, research is needed to address knowledge gaps, particularly regarding the relevance and extent of diet-induced hyperkalaemia in patients undergoing dialysis.},
address = {Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. juan.jesus.carrero@ki.se.; Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Nephrology and Mineral Metabolism Department, Instituto Nacional de Ciencias M{\'e}dicas y Nutrici{\'o}n Salvador, Zubir{\'a}n, Mexico.; Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Nephrology Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy.; Service de N{\'e}phrologie Transplantation Dialyse, Centre Hospitalier Universitaire de Bordeaux et Aurad-Aquitaine, Bordeaux, France.; Departments of Medicine and Health Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.; Nephrology and Mineral Metabolism Department, Instituto Nacional de Ciencias M{\'e}dicas y Nutrici{\'o}n Salvador, Zubir{\'a}n, Mexico.; Department of Nephrology, Hospital Universitari Dr Peset, Universitat de Val{\`e}ncia, Val{\`e}ncia, Spain.; Renal transplant unit, Pellegrin Hospital, Bordeaux, France.; Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.; Nephrologie, Centre Hospitalier Le Mans, Le Mans, France.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Nephrology, Baskent University School of Medicine, Ankara, Turkey.; Department of Nephrology, Universit{\'e}de Lyon, Carmen, Hospital Lyon-Sud, Lyon, France.},
auid = {ORCID: 0000-0002-8891-9892; ORCID: 0000-0002-4458-8358; ORCID: 0000-0003-3356-6791; ORCID: 0000-0001-9374-0152; ORCID: 0000-0002-7072-195X; ORCID: 0000-0002-8995-936X; ORCID: 0000-0001-9153-5155; ORCID: 0000-0002-6788-5427; ORCID: 0000-0002-2632-4009; ORCID: 0000-0001-8645-1627; ORCID: 0000-0002-9707-7199},
author = {Carrero, Juan J and Gonz{\'a}lez-Ortiz, Ailema and Avesani, Carla M and Bakker, Stephan J L and Bellizzi, Vincenzo and Chauveau, Philippe and Clase, Catherine M and Cupisti, Adamasco and Espinosa-Cuevas, Angeles and Molina, Pablo and Moreau, Karine and Piccoli, Giorgina B and Post, Adrian and Sezer, Siren and Fouque, Denis},
crdt = {2020/06/13 06:00},
date = {2020 Sep},
date-added = {2023-01-28 12:43:39 +0000},
date-modified = {2023-06-03 19:57:13 +0100},
dcom = {20201106},
dep = {20200611},
doi = {10.1038/s41581-020-0297-2},
edat = {2020/06/13 06:00},
issn = {1759-507X (Electronic); 1759-5061 (Linking)},
jid = {101500081},
journal = {Nat Rev Nephrol},
jt = {Nature reviews. Nephrology},
keywords = {Plant-Based Diet},
language = {eng},
lid = {10.1038/s41581-020-0297-2 {$[$}doi{$]$}},
lr = {20210217},
mh = {Acid-Base Equilibrium; Diet, Healthy; Diet, Mediterranean; *Diet, Vegetarian; Dietary Approaches To Stop Hypertension; Dietary Fats, Unsaturated; Dietary Fiber; Disease Progression; Humans; Hyperkalemia/etiology; Phosphorus, Dietary; Plant Proteins, Dietary; Potassium, Dietary/adverse effects; Renal Dialysis; Renal Insufficiency, Chronic/*diet therapy/metabolism},
mhda = {2020/11/11 06:00},
month = {Sep},
number = {9},
own = {NLM},
pages = {525--542},
phst = {2020/04/23 00:00 {$[$}accepted{$]$}; 2020/06/13 06:00 {$[$}pubmed{$]$}; 2020/11/11 06:00 {$[$}medline{$]$}; 2020/06/13 06:00 {$[$}entrez{$]$}},
pii = {10.1038/s41581-020-0297-2},
pl = {England},
pmid = {32528189},
pst = {ppublish},
pt = {Journal Article; Research Support, Non-U.S. Gov't; Review},
rn = {0 (Dietary Fats, Unsaturated); 0 (Dietary Fiber); 0 (Phosphorus, Dietary); 0 (Plant Proteins, Dietary); 0 (Potassium, Dietary)},
sb = {IM},
status = {MEDLINE},
title = {Plant-based diets to manage the risks and complications of chronic kidney disease.},
volume = {16},
year = {2020},
bdsk-url-1 = {https://doi.org/10.1038/s41581-020-0297-2}}