Metabolic acidosis and the progression of chronic kidney disease. (bibtex)
by Wei Chen and Matthew K Abramowitz
Abstract:
Metabolic acidosis is a common complication of chronic kidney disease. Accumulating evidence identifies acidosis not only as a consequence of, but as a contributor to, kidney disease progression. Several mechanistic pathways have been identified in this regard. The dietary acid load, even in the absence of overt acidosis, may have deleterious effects. Several small trials now suggest that the treatment of acidosis with oral alkali can slow the progression of kidney disease.
Reference:
Metabolic acidosis and the progression of chronic kidney disease. (Wei Chen and Matthew K Abramowitz), In BMC Nephrol, volume 15, 2014.
Bibtex Entry:
@article{Chen:2014aa,
	abstract = {Metabolic acidosis is a common complication of chronic kidney disease. Accumulating evidence identifies acidosis not only as a consequence of, but as a contributor to, kidney disease progression. Several mechanistic pathways have been identified in this regard. The dietary acid load, even in the absence of overt acidosis, may have deleterious effects. Several small trials now suggest that the treatment of acidosis with oral alkali can slow the progression of kidney disease.},
	address = {Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA. matthew.abramowitz@einstein.yu.edu.},
	author = {Chen, Wei and Abramowitz, Matthew K},
	crdt = {2014/04/09 06:00},
	date = {2014 Apr 3},
	date-added = {2023-01-28 08:11:53 +0000},
	date-modified = {2023-05-24 18:08:22 +0100},
	dcom = {20141206},
	dep = {20140403},
	doi = {10.1186/1471-2369-15-55},
	edat = {2014/04/09 06:00},
	gr = {T32 DK007110/DK/NIDDK NIH HHS/United States; 1 KL2 TR001071-01/TR/NCATS NIH HHS/United States; UL1 TR001073/TR/NCATS NIH HHS/United States; 1 TL1 TR001072-01/TR/NCATS NIH HHS/United States; 1 UL1 TR001073-01/TR/NCATS NIH HHS/United States},
	issn = {1471-2369 (Electronic); 1471-2369 (Linking)},
	jid = {100967793},
	journal = {BMC Nephrol},
	jt = {BMC nephrology},
	keywords = {Diet, Metabolic Acidosis},
	language = {eng},
	lid = {10.1186/1471-2369-15-55 {$[$}doi{$]$}},
	lr = {20220331},
	mh = {Acidosis/diagnosis/*etiology/*therapy; Citrates/therapeutic use; Diet Therapy/methods; Disease Progression; Humans; Renal Insufficiency, Chronic/*complications/diagnosis/*therapy; Risk Factors; Sodium Bicarbonate/therapeutic use; Sodium Citrate; Survival Rate; Treatment Outcome},
	mhda = {2014/12/15 06:00},
	month = {Apr},
	own = {NLM},
	pages = {55},
	phst = {2014/01/08 00:00 {$[$}received{$]$}; 2014/03/31 00:00 {$[$}accepted{$]$}; 2014/04/09 06:00 {$[$}entrez{$]$}; 2014/04/09 06:00 {$[$}pubmed{$]$}; 2014/12/15 06:00 {$[$}medline{$]$}},
	pii = {1471-2369-15-55},
	pl = {England},
	pmc = {PMC4233646},
	pmid = {24708763},
	pst = {epublish},
	pt = {Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't},
	rn = {0 (Citrates); 1Q73Q2JULR (Sodium Citrate); 8MDF5V39QO (Sodium Bicarbonate)},
	sb = {IM},
	status = {MEDLINE},
	title = {Metabolic acidosis and the progression of chronic kidney disease.},
	volume = {15},
	year = {2014},
	bdsk-url-1 = {https://doi.org/10.1186/1471-2369-15-55}}
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