Homocysteine, vitamin B12 and folate level: Possible risk factors in the progression of chronic heart and kidney disorders (bibtex)
by Aditi Mohan, Ravi Kumar, Vivek Kumar and Mahendra Yadav
Abstract:
Cobalamin is an essential molecule for humans; it is exceptionally important for various body functions, including deoxyribonucleic acid synthesis and cellular energy production. Vegans are more vulnerable to vitamin B12 deficiency than natives with moderate consumption of animal dietary supplements or people with inadequate nutritional patterns. However, the long-term effects of sub-medical deficiency have not been thoroughly studied, but they may have a negative impact on the cardiovascular system, pregnancy outcomes, and vascular, renal, cognitive, bone, and eye health. Alongside the statin remedy, that is a powerful approach for CVD prevention. Another approach is related to the B nutrition substitution remedy with folic acid, and vitamins B6 and B12 are extensively practised nowadays. There is a tremendous interest in plasma homocysteine (tHcy) as a cardiovascular hazard factor. However, current research in the field of its prevention is more inclined toward confirming the benefit of a tHcy-reducing remedy with nutrition B12. Thus, while folic acid fortification is primarily aimed at reducing neural-tube defects, it may also play a significant role in the primary prevention of CVD by lowering tHcy. Folate and B-vitamins play important roles in CVD prevention and nutrition policy implementation. Patients affected by Chronic Kidney Disease (CKD) or end-stage Stage Renal Disease (ESRD) experience a tremendous cardiovascular threat that may also further lead to death. As a result, routine monitoring of vitamin B12 levels is likely to be beneficial for the early detection and treatment of metabolic vitamin B12 deficiency, as well as the prevention of heart-related diseases.
Reference:
Homocysteine, vitamin B12 and folate level: Possible risk factors in the progression of chronic heart and kidney disorders (Aditi Mohan, Ravi Kumar, Vivek Kumar and Mahendra Yadav), In Curr Cardiol Rev, 2023.
Bibtex Entry:
@article{Mohan:2023aa,
	abstract = {Cobalamin is an essential molecule for humans; it is exceptionally important for various body functions, including deoxyribonucleic acid synthesis and cellular energy production. Vegans are more vulnerable to vitamin B12 deficiency than natives with moderate consumption of animal dietary supplements or people with inadequate nutritional patterns. However, the long-term effects of sub-medical deficiency have not been thoroughly studied, but they may have a negative impact on the cardiovascular system, pregnancy outcomes, and vascular, renal, cognitive, bone, and eye health. Alongside the statin remedy, that is a powerful approach for CVD prevention. Another approach is related to the B nutrition substitution remedy with folic acid, and vitamins B6 and B12 are extensively practised nowadays. There is a tremendous interest in plasma homocysteine (tHcy) as a cardiovascular hazard factor. However, current research in the field of its prevention is more inclined toward confirming the benefit of a tHcy-reducing remedy with nutrition B12. Thus, while folic acid fortification is primarily aimed at reducing neural-tube defects, it may also play a significant role in the primary prevention of CVD by lowering tHcy. Folate and B-vitamins play important roles in CVD prevention and nutrition policy implementation. Patients affected by Chronic Kidney Disease (CKD) or end-stage Stage Renal Disease (ESRD) experience a tremendous cardiovascular threat that may also further lead to death. As a result, routine monitoring of vitamin B12 levels is likely to be beneficial for the early detection and treatment of metabolic vitamin B12 deficiency, as well as the prevention of heart-related diseases.},
	author = {Mohan, Aditi and Kumar, Ravi and Kumar, Vivek and Yadav, Mahendra},
	date-added = {2023-06-10 14:05:57 +0100},
	date-modified = {2023-07-21 07:18:53 +0100},
	doi = {10.2174/1573403X19666230209111854},
	journal = {Curr Cardiol Rev},
	journal-full = {Current cardiology reviews},
	keywords = {Vitamin B12; CKD},
	month = {Feb},
	pmid = {36757031},
	pst = {aheadofprint},
	title = {Homocysteine, vitamin B12 and folate level: Possible risk factors in the progression of chronic heart and kidney disorders},
	year = {2023},
	bdsk-url-1 = {https://doi.org/10.2174/1573403X19666230209111854}}
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