Exercise capacity in pediatric patients with end-stage renal disease (bibtex)
by Anirut Pattaragarn, Bradley A Warady and Richard J Sabath
Abstract:
OBJECTIVE: To evaluate the correlation between exercise capacity and hemoglobin in pediatric patients with end-stage renal disease (ESRD) treated with automated peritoneal dialysis (APD) and hemodialysis. DESIGN: Prospective case-control study and retrospective review. SETTING: Dialysis summer camp and Children's Mercy Hospital exercise laboratory. PARTICIPANTS: Prospective evaluation conducted with 14 patients (9 males, mean age 14.5 +/- 2.5 years) who received either home APD (5 patients) or in-center hemodialysis (9 patients), and 8 healthy age-matched controls. Retrospective data derived from 10 children (7 males, mean age 12.3 +/- 3.3 years), all of whom received APD. INTERVENTION: Maximal treadmill evaluation conducted with each patient and control. The hemoglobin value of each patient was also assessed. MAIN OUTCOME MEASURES: Comparison of the following data generated during treadmill protocol: peak heart rate, blood pressure, oxygen saturation, treadmill time, oxygen consumption (VO2), ventilation (Ve), oxygen consumption at anaerobic threshold (VO2AT), and respiratory exchange ratio. RESULTS: The hemoglobin value of the current patient group (12.8 +/- 1.6 g/dL) was significantly greater than the previously studied patients (10.5 +/- 1.1 g/dL) (p = 0.001). Treadmill time, VO2, and VO2AT were significantly lower in both groups of dialysis patients compared to the control subjects (p < 0.05). No differences were noted in any of these variables when comparing these two groups of dialysis patients only. CONCLUSION: The exercise capacity of pediatric dialysis patients is significantly poorer than that of healthy children, an outcome apparently related to factors other than normalization of the hemoglobin value.
Reference:
Exercise capacity in pediatric patients with end-stage renal disease (Anirut Pattaragarn, Bradley A Warady and Richard J Sabath), In Perit Dial Int, volume 24, 2004.
Bibtex Entry:
@article{Pattaragarn:2004aa,
	abstract = {OBJECTIVE: To evaluate the correlation between exercise capacity and hemoglobin in pediatric patients with end-stage renal disease (ESRD) treated with automated peritoneal dialysis (APD) and hemodialysis.
DESIGN: Prospective case-control study and retrospective review.
SETTING: Dialysis summer camp and Children's Mercy Hospital exercise laboratory.
PARTICIPANTS: Prospective evaluation conducted with 14 patients (9 males, mean age 14.5 +/- 2.5 years) who received either home APD (5 patients) or in-center hemodialysis (9 patients), and 8 healthy age-matched controls. Retrospective data derived from 10 children (7 males, mean age 12.3 +/- 3.3 years), all of whom received APD.
INTERVENTION: Maximal treadmill evaluation conducted with each patient and control. The hemoglobin value of each patient was also assessed.
MAIN OUTCOME MEASURES: Comparison of the following data generated during treadmill protocol: peak heart rate, blood pressure, oxygen saturation, treadmill time, oxygen consumption (VO2), ventilation (Ve), oxygen consumption at anaerobic threshold (VO2AT), and respiratory exchange ratio.
RESULTS: The hemoglobin value of the current patient group (12.8 +/- 1.6 g/dL) was significantly greater than the previously studied patients (10.5 +/- 1.1 g/dL) (p = 0.001). Treadmill time, VO2, and VO2AT were significantly lower in both groups of dialysis patients compared to the control subjects (p < 0.05). No differences were noted in any of these variables when comparing these two groups of dialysis patients only.
CONCLUSION: The exercise capacity of pediatric dialysis patients is significantly poorer than that of healthy children, an outcome apparently related to factors other than normalization of the hemoglobin value.},
	author = {Pattaragarn, Anirut and Warady, Bradley A and Sabath, Richard J},
	date-added = {2023-01-09 20:12:20 +0000},
	date-modified = {2023-01-09 20:12:31 +0000},
	journal = {Perit Dial Int},
	journal-full = {Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis},
	keywords = {Physical Activity},
	mesh = {Adolescent; Anaerobic Threshold; Blood Pressure; Case-Control Studies; Child; Exercise Test; Exercise Tolerance; Female; Heart Rate; Hemoglobins; Humans; Kidney Failure, Chronic; Male; Prospective Studies; Renal Dialysis},
	number = {3},
	pages = {274-80},
	pmid = {15185776},
	pst = {ppublish},
	title = {Exercise capacity in pediatric patients with end-stage renal disease},
	volume = {24},
	year = {2004}}
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